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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Reducing Aspirin Dosage Help In Reducing Easy Bruising?

Hi, I m a 72 year old male who had triple bypass surgery 28 years ago. At that time I was prescribed Metoprolol tartrate 50mg x 2 daily, Lisinopril 40 mg x 1, lipitor 40 mg x 1, and 325 coated aspirin x 1. I am an active swimmer 1.5 miles 3 times a week. 6 months ago I reduced and then quit taking the Lisinopril because my blood pressure was getting too low, Now my B/P is consistently around 117/64 each day. My question concerns the 325 mg aspirin--I seem to bruise quite easily and wanted to reduce the aspirin to 81 mg. I m also type 2 diabetic but control it fairly well (6.5 A1C). Will reducing the aspirin help? Thank you.
Mon, 23 Jul 2018
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General & Family Physician,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

Aspirin causes several different effects in the body like reduction of inflammation, analgesia, prevention of clotting and reduction of fever.
Aspirin's ability to suppress the production of Prostaglandins and Thromboxane is due to its irreversible inactivation of the Cyclooxygenase (COX) enzyme.
Low-dose, long-term use of aspirin irreversibly blocks the formation of Thromboxane A2 in platelets, producing an inhibitory effect on platelet aggregation.
A side-effect of aspirin mechanism is that the ability of the blood to clot is reduced, and can cause excessive bleeding.
You can consult your doctor for appropriate dose to be taken if the present dose is causing side effects like easy bruising.

Hope the information provided helps.
All the best.
Regards,
Dr.Ashakiran.S.
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Does Reducing Aspirin Dosage Help In Reducing Easy Bruising?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Aspirin causes several different effects in the body like reduction of inflammation, analgesia, prevention of clotting and reduction of fever. Aspirin s ability to suppress the production of Prostaglandins and Thromboxane is due to its irreversible inactivation of the Cyclooxygenase (COX) enzyme. Low-dose, long-term use of aspirin irreversibly blocks the formation of Thromboxane A2 in platelets, producing an inhibitory effect on platelet aggregation. A side-effect of aspirin mechanism is that the ability of the blood to clot is reduced, and can cause excessive bleeding. You can consult your doctor for appropriate dose to be taken if the present dose is causing side effects like easy bruising. Hope the information provided helps. All the best. Regards, Dr.Ashakiran.S.