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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Taking Allopurinol And Colchicine Together Cause Fatigue And Pain?

I have just started allupurinol and colchicine as I have MS and Mixed connective it’s disease. My Uric acid is normal or below but I have gout and rheumatoid. I am very fatigued and in pain and am wonder if the two new drug as are impacting me or is it simply MS.
Tue, 10 Jul 2018
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General & Family Physician,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

There are no known interactions between these two medications. Colchicine can cause muscle weakness or pain in some persons so it is possible that it may be contributing to your symptoms. You may need to speak to your doctor about the symptoms that you are experiencing.

Hope I have answered your query.
Let me know if I can assist you further.





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Does Taking Allopurinol And Colchicine Together Cause Fatigue And Pain?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. There are no known interactions between these two medications. Colchicine can cause muscle weakness or pain in some persons so it is possible that it may be contributing to your symptoms. You may need to speak to your doctor about the symptoms that you are experiencing. Hope I have answered your query. Let me know if I can assist you further.