hello thanks for posting your query I would be pleased to answer your question Crohn s disease does present with gross pathological changes in the intestines and can be picked up by the colonoscopy . However , it is also very important to remember that a biopsy of the intestine during the colonoscopy gives a perfect diagnosis . Your clinical correlation is very important and you need to surely get the diagnosis rechecked with a second opinion . You symptoms are very suggestive of Crohn s or an inflammatory bowel disease. Thanks and Take care