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Had Ductal Breast Cancer. On Radiation & Tamoxifin. Had Discontinued. Diagnosed With Spinal Tumors. Caused By SERM?

My sister was diagnosed and treated with radiation and tamoxifin for ductal breast cancer. She talked about discontinuing the SERM a couple months after starting it. She was diagnosed with spinal tumors last week. She claims to have stopped taking the medication in March after her back pain started. What is the probability of spinal tumors developing while taking the SERM?


posted on Sun, 7 Jul 2013
Twitter Mon, 8 Jul 2013 Answered on
Twitter Tue, 9 Jul 2013 Last reviewed on
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,

SERM stands for selective estrogen modulator.
SERM drugs have a an estrogenic and anti-estrogenic side effect on different organs.
The main organs affected by SERM are uterus and breast.
The newly developed drugs of SERM group have anti-estrogenic effect on the uterus but an estrogenic effect on the breast.
Spinal tumors are unlikely to be due to treatment by SERM.
Get the relevant investigation done after consulting your treatment.

Thanks and take care
Dr Shailja P Wahal
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Had Ductal Breast Cancer. On Radiation & Tamoxifin. Had Discontinued. Diagnosed With Spinal Tumors. Caused By SERM?

Hello and welcome to HCM, SERM stands for selective estrogen modulator. SERM drugs have a an estrogenic and anti-estrogenic side effect on different organs. The main organs affected by SERM are uterus and breast. The newly developed drugs of SERM group have anti-estrogenic effect on the uterus but an estrogenic effect on the breast. Spinal tumors are unlikely to be due to treatment by SERM. Get the relevant investigation done after consulting your treatment. Thanks and take care Dr Shailja P Wahal