Hello Thanks for your query. PCOS is characterized by anovulation, and irregular periods. The periods are delayed, and there is endometrial hyperplasia ( overgrowth of the lining of the uterus ) when one does menstruate, the period is heavy and painful. Duphaston is given to regulate the cycle, however, it is a progesterone preparation that further acts on the lining of the uterus to make it thicker. Hence it is natural, for the first time, to have a heavy and painful period. You should definitely consult your gynecologist for further tests such as hormonal tests - FSH, LH, thyroid profile, adrenal profile, blood sugars etc. Also, weight loss, lifestyle management are important aspects of treating PCOS. Various other treatments based on your reports maybe given, also. Take care