I was diagnosed with PCOS about 5 years ago. I don t feel that any of the medications have helped my initial complaints - hirsutism, general fatigue, difficulty losing weight (I am morbidly obese, clinically, even following weight loss surgery, and though I know I am not the best with my diet and exercise, I do try but have minimal results). I took aldactone for the facial hair for a year. It just made me more tired, no relief of hair growth. I take a low dosage birth control pill. My lab work showed no tumors on my adrenals, high DHEAs (like, 5x what they should be), normal thyroid function, and no indication of diabetes. My boyfriend seems to think I exhibit symptoms of Cushing s Disease. I do have the buffalo hump and a very round face. How should I pursue this? Do you think this is a possibility that should be ruled in or ruled out?