Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.
It seems your grandmother is suffering from
Osteoarthritis.
Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), and
Cyclooxygenase-2 (COX-2) Inhibitors can be used for pain relief. Acetaminophen (
paracetamol) is the initial
analgesic of choice for patients with OA in knees, hips, or hands. For some patients, it is adequate to control symptoms, in which case more toxic drugs such as NSAIDs can be avoided. Gel or topical solution of NSAIDs can be applied .Topical NSAIDs are slightly less efficacious than oral agents, but have far fewer GI and systemic side effects.
When medical therapies have failed and the patient has
an unacceptable reduction in their quality of life and ongoing pain and
disability, then at least for knee and hip OA, total joint arthro-plasty is indicated.
For patients with symptomatic knee or hip OA who have not had an adequate response to the medical treatments and are either unwilling to undergo or are not candidates for total joint arthroplasty, opioid analgesics (Tramadol) have shown modest efficacy and can be tried.
Regards,
Dr. T.K. Biswas M.D.