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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can Severe Withdrawal Symptoms Like Tingling, Anxiety, And Weakness After Switching From Deanxit To Wellbutrin With Escitalopram Be Treated?

I was on deanxit for 2 years with escitolopram 20 , my doctor stoped deanxit due to its side efficts and put me on wellbutrin 150 my with escitolopram 20 mg, it has been 12, 13 days and facing severe withdrawl symptoms like needles and tingles sensation in Arms and legs, Anxiety and weakness, what should i do with these symptoms Thanks and Regards
posted on Thu, 2 Nov 2023
Twitter Tue, 12 Aug 2025 Answered on
Twitter Tue, 2 Sep 2025 Last reviewed on
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General & Family Physician 's  Response
Hello,

Because Deanxit has both an antidepressant and an antipsychotic component, stopping it abruptly even when replaced with other antidepressants can cause significant withdrawal effects. It can take 4–6 weeks for your system to adjust fully after such a switch. Since the withdrawal symptoms are impacting your daily life, you are advised to keep your treating doctor informed regarding it.

Informing your treating doctor who has prescribed you medicines is important as he should consider prescribing another medication to bridge the withdrawal period or adjust your Wellbutrin dose or add a short-term anti-anxiety / nerve stabilizer so that you are comfortable. Tingling and weakness can sometimes come from vitamin deficiencies (B12, folate, vitamin D) or other nerve issues.

You may be referred to a neurologist for further treatment. Drink enough fluids to remain well hydrated. Eat regular, balanced meals. Avoid a sedentary lifestyle and be active. Do gentle physical activity like walking and stretching. It will improve nerve symptoms. Avoid excess caffeine, as Wellbutrin already stimulates the nervous system.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Nupur K., General & Family Physician
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How Can Severe Withdrawal Symptoms Like Tingling, Anxiety, And Weakness After Switching From Deanxit To Wellbutrin With Escitalopram Be Treated?

Hello, Because Deanxit has both an antidepressant and an antipsychotic component, stopping it abruptly even when replaced with other antidepressants can cause significant withdrawal effects. It can take 4–6 weeks for your system to adjust fully after such a switch. Since the withdrawal symptoms are impacting your daily life, you are advised to keep your treating doctor informed regarding it. Informing your treating doctor who has prescribed you medicines is important as he should consider prescribing another medication to bridge the withdrawal period or adjust your Wellbutrin dose or add a short-term anti-anxiety / nerve stabilizer so that you are comfortable. Tingling and weakness can sometimes come from vitamin deficiencies (B12, folate, vitamin D) or other nerve issues. You may be referred to a neurologist for further treatment. Drink enough fluids to remain well hydrated. Eat regular, balanced meals. Avoid a sedentary lifestyle and be active. Do gentle physical activity like walking and stretching. It will improve nerve symptoms. Avoid excess caffeine, as Wellbutrin already stimulates the nervous system. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Nupur K., General & Family Physician