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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Serious Is Diffuse Cerebral And Cerebellar Volume Loss?

I was informed that: 1. Mild to moderate diffuse cerebral and cerebellar volume loss, somewhat greater than expected for the patient s age. 2. Small incidental curvilinear posterior pericallosal lipoma (benign tumor of fatty tissue) 3. Otherwise normal MRI of the brain. How serious is all this? I m very concerned.
Mon, 20 Jul 2015
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Neurologist,  's  Response
I read your question carefully and I understand your concern.

Everyone of us after our twenties starts to lose brain cells, hence brain volume, it's part of aging. With the passing of the years as the loss adds up it will start to become visible on MRI. So how abnormal that finding is depends on your age which unfortunately you do not mention.
Judging by the report it would seem it is more than the average for someone your age. It says somewhat so it's not allarmingly more and it is a somewhat subjective estimation anyway.
I don't know why you had the MRI, but that finding shouldn't be causing any symptoms. At worst it may indicate that your brain is aging quickly, might have a greater predisposition for cognitive decline in the future, but that isn't necessarily so, there isn't an exact correlation between brain mass and cognitive performance.

I hope to have been of help.
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How Serious Is Diffuse Cerebral And Cerebellar Volume Loss?

I read your question carefully and I understand your concern. Everyone of us after our twenties starts to lose brain cells, hence brain volume, it s part of aging. With the passing of the years as the loss adds up it will start to become visible on MRI. So how abnormal that finding is depends on your age which unfortunately you do not mention. Judging by the report it would seem it is more than the average for someone your age. It says somewhat so it s not allarmingly more and it is a somewhat subjective estimation anyway. I don t know why you had the MRI, but that finding shouldn t be causing any symptoms. At worst it may indicate that your brain is aging quickly, might have a greater predisposition for cognitive decline in the future, but that isn t necessarily so, there isn t an exact correlation between brain mass and cognitive performance. I hope to have been of help.