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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Come Off Zyprexa Safely Without Side Effects?

How to come off Zyprexa safely? I was wrongly prescribed Zyprexa to treat my PDST. After a sexual harassment at college ( four years ago), I was irritable and feeling harmed. I did not have any psychosis or halluciations, and though it was difficult time, I was sleeping and eating well. The doctor I saw, however, prescribed me with Zyprexa. This drug has completely changed by my being, personality, and life in the course of three years. It completely blunts my emotions. I used to be a very happy, positive and engaging young person. But the drug has made me indifferent to all things. I feel like a zombie, a walking dead, losing all interests and joy in life. Two months into taking the medicine, I gained 30 pounds. I had never had sleeping problems, but shortly after I took Zyprexa, I experienced insomnia when not taking it. ( that s the main reason why I keep taking it, because without taking it I could not sleep.) What s more, Zyprexa has completely killed my libido. I haven t had intimate relation with my husband since shortly after I took the drug regularly. This July, after suffering so much from it, I tried to come off it on my own and it proved to be disastrous. We cut down from 3.75 to 0.60mg in a span of one month. The reduction was ok; I did not experience any anxiety, racing thoughts or any thing. But when I went .60 to 0, I experienced terrible insomnia for almost a month. I took 1mg of Ativan, but it worked some nights and didn t work for most nights. I had great difficulties falling asleep and the insomnia was really trying. We were in India when this happened. With the insomnia prolonged and withdrawl from Zyprexa, I became increasingly unstable. Two weeks into 0 on Zyprexa, I started to have mood swings and uncontrollable thoughts, keeping thinking about Zyprexa, how I was led to it and all the unpleasant things that happened it the past to the point these thoughts made me suicidal, which I had never thought in my life. I also felt very low and weak, a feeling of depression I never had had before. Facing with a very trying situation, my husband and I had to make decision, whether get me hospitalized or get back on the Zyprexa. I don t have any mental problems; I was basically a normal person who was wrongly prescribed and stuck on a very strong anti-psychotic drug for such a long time. I did not want to go to hospital because I knew I would be put on more drugs if I go. So we went back on 3.75 Zyprexa and 1mg of Ativan. After experiencing such a terrible withdrawl, I m feeling helpless. My question is, how can I come off the drug safely without being hurt again? How can I cope with insomnia and disturbing thoughts when coming off it?
Mon, 12 Jan 2015
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General & Family Physician 's  Response
Hello,
I have read your query and really feel very sad for the state you are in.
ZYPREXA is a very serious antipsychotic drug and it's withdrawal symptoms are really very debilitating.
Of all the antipsychotic drugs,ZYPREXA causes maximum weight gain.
You really have to be very slow in withdrawing from this drug.
Longer a person has used this drug,longer it takes to come out of it.
The best is to withdraw the drug 10% every month.
By slowly reducing your dose your body shall get time to accommodate and adjust to lower doses.
I know it is going to take many months in coming out of it but frankly speaking this is the only way going further.
Thanks
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How To Come Off Zyprexa Safely Without Side Effects?

Hello, I have read your query and really feel very sad for the state you are in. ZYPREXA is a very serious antipsychotic drug and it s withdrawal symptoms are really very debilitating. Of all the antipsychotic drugs,ZYPREXA causes maximum weight gain. You really have to be very slow in withdrawing from this drug. Longer a person has used this drug,longer it takes to come out of it. The best is to withdraw the drug 10% every month. By slowly reducing your dose your body shall get time to accommodate and adjust to lower doses. I know it is going to take many months in coming out of it but frankly speaking this is the only way going further. Thanks