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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Alzheimer S Disease A Genetic Disorder?

What is the genetic factors involved with Alzeimers? My wife, 84, has suffered with Alzeimers for five years and is currently in an assisted living/hospice unit. Her mother died at 95 with the same disease; her sister is 92, similarly diagnosed, and in assisted living for six years. This is why I feel that, at least, in this case there is a definite indication of a genetic factor involved. What do you think? Rich Hight , Toms River, N.J. Thank you!
Tue, 17 Jul 2018
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Internal Medicine Specialist,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

Some times Alzheimer's disease strikes early and fairly often in some families often enough that experts single it out as a separate form of the disease. It’s called early-onset familial Alzheimer's disease.
People with Down syndrome have an extra copy of chromosome 21. As they grow older, they often get Alzheimer’s symptoms, though at a younger age than others who get the disease. Still more genes on study , still have more doubts please consult your doctor he will examine and treat you accordingly.

Hope I have answered your query.
Let me know if I can assist you further.
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Is Alzheimer S Disease A Genetic Disorder?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Some times Alzheimer s disease strikes early and fairly often in some families often enough that experts single it out as a separate form of the disease. It’s called early-onset familial Alzheimer s disease. People with Down syndrome have an extra copy of chromosome 21. As they grow older, they often get Alzheimer’s symptoms, though at a younger age than others who get the disease. Still more genes on study , still have more doubts please consult your doctor he will examine and treat you accordingly. Hope I have answered your query. Let me know if I can assist you further.