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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Take Aleve With Sulfasalazine?

I started sulfasalazine therapy about 2 month ago. I m taking 2 500mg twice a day. It is working well on my even I still feel some mild pain. The thing is I just go a neck spasm and I need some strong antinflamatory. Long ago I used celebrex because it was the only thing that worked form me. Right now I don t have celebrex, but I do have some Aleve. Is it safe to take Aleve with the sulfasalazine? I also take glimepiride, metformin, omeprazole and losartan.
posted on Sun, 12 Jul 2015
Twitter Wed, 8 Jul 2020 Answered on
Twitter Thu, 16 Jul 2020 Last reviewed on
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General & Family Physician 's  Response
Hi,

Aleve contains Naproxen which is also an anti-inflammatory drug like Celebrex. Both Sulfasalazine and pain killers when taken together can affect renal function in the long run. Hence I would suggest you to restrict the drug use for shorter duration and check your renal function regularly.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Dorina Gurabardhi, General & Family Physician