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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Take Ropinirole, Eszopiclone, Ranitidine And Cephalexin Together?

I am taking 5 medications starting tomorrow. Could you tell me if it’s safe to take them and would not cause major problems. Ropinirole 2mg
Folic Acid 1mg
Eszopiclone 3mg
Ranitidine 300mg
Cephalexin 500mg - new one capsule three times daily for 5 day
Sat, 3 Nov 2018
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Internal Medicine Specialist 's  Response
Hi,

CYP1A2 inhibitors like Ranitidine can decrease metabolic clearance of Ropinirole. Ropinirole dosage adjustment may be needed if the CYP1A2 inhibitor is started or stopped during treatment with Ropinirole.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Tushar Kanti Biswas,
Internal Medicine Specialist
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Is It Safe To Take Ropinirole, Eszopiclone, Ranitidine And Cephalexin Together?

Hi, CYP1A2 inhibitors like Ranitidine can decrease metabolic clearance of Ropinirole. Ropinirole dosage adjustment may be needed if the CYP1A2 inhibitor is started or stopped during treatment with Ropinirole. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Tushar Kanti Biswas, Internal Medicine Specialist