Hello, No, Sibellium does not cause knee pain. Detailed Answer: Sibelium 10 mg tablet is prescribed to patients for the treatment of the following medical conditions: •     The most important reason for the prescription of the Sibelium 10 mg tablet is its ability to prevent migraine headaches. •     Reduction of the intensity of migraine headaches. •     The decrease in the number of occurrences of migraine headaches. •     Decrease or eliminate the patient’s sensitivity to light, noise and certain smells. •     Treatment and prevention of vestibular disorders (medical disorders related to ears and the brain) •     Prevention of vertigo, of central as well as the peripheral origin. •     Side effects: Ringing or buzzing of ears •     The tingling sensation of hands and feet •     Numbness in hands and feet •     Depression and mood swings •     Weight gain and/or increased appetite •     Constipation •     Excessive sleepiness/fatigue •     Insomnia •     Muscle pain and cramps •     Rhinitis •     Inflammation of faces, hands, and feet •     Disturbance in menstrual cycle observed in female patients •     Excessive sweating, hot flashes •     Blocked or runny nose •     Elevated levels of liver enzymes If these effects continue, please contact your doctor. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Enton Dore, General & Family Physician