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Is Pregnancy Possible With Perimenopausal And Follicle Problems?
Hi, I am 37 & want to have a 2nd baby. I was diagnosed w/ IgA Nephropathy about 6 yrs. ago & had a normal, healthy delivery 3 yrs. ago. I'm now having trouble getting pregnant & had to consult a fertility specialist. The specialist said I'm perimenopausal since my estrogen level is 69.5 & FSH is 10. I have multiple follicles, with only 4 being over 1cm. What are my chances of getting pregnant again & how will Clomid or any other fertility drug effect my kidneys? Many thanks!
posted on
Thu, 13 Mar 2014
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Mon, 11 Aug 2025
Answered on
Mon, 1 Sep 2025
Last reviewed on
Hello,
Pregnancy is possible for you, especially with fertility drugs, but your window is narrowing. With careful monitoring, Clomid and medicines that can be used safely. Act sooner rather than later as both perimenopause and IgA nephropathy add time sensitivity. Check partner’s fertility factors to ensure no additional delays. Your partner is advised to get his semen analysis done.
Get clinically evaluated by your fertility specialist; low intensity stimulation will be the best for you. You will be referred to a nephrologist as you need to get done kidney function tests. Monitor kidney lab tests like creatinine, eGFR, urine protein, etc., before and during fertility treatment. The main concern isn’t the drug’s direct kidney toxicity, but the indirect risks if your kidney function is already fragile.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Nupur K., General & Family Physician
Pregnancy is possible for you, especially with fertility drugs, but your window is narrowing. With careful monitoring, Clomid and medicines that can be used safely. Act sooner rather than later as both perimenopause and IgA nephropathy add time sensitivity. Check partner’s fertility factors to ensure no additional delays. Your partner is advised to get his semen analysis done.
Get clinically evaluated by your fertility specialist; low intensity stimulation will be the best for you. You will be referred to a nephrologist as you need to get done kidney function tests. Monitor kidney lab tests like creatinine, eGFR, urine protein, etc., before and during fertility treatment. The main concern isn’t the drug’s direct kidney toxicity, but the indirect risks if your kidney function is already fragile.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Nupur K., General & Family Physician
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