Hi, Welcome to Healthcare Magic! I understand that the medicines were changed because of the complaint of burning sensation in abdomen, neck and rest of the body. In my experience, this may not have been due to the medicines she was on, that is, fluoxetine, imipramine and alprazolam, but could have been due to other reasons like acidity or post-menopausal hot flushes. Out of her present medications, Pari CR plus is of the same class as fluoxetine and Spectra as imipramine. I would have been able to advise you better if you could have let me know since when she was on the old medicines and when did the burning sensation start. I would also have liked to know whether the burning sensation improved on changing the medicines. If it hasn t, then you should ask your doctor to look for other reasons for the burning sensation and request him to change over to the previous medicines. Hope this answers your query. Best wishes. Dr Preeti Parakh MD Psychiatry