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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffer With Beta-Thalassemia Minor As Well As G6PD Deficiency. Are There Any Coupled Effects?

Hi, I understand that I have both Beta-Thalassemia Minor as well as G6PD Deficiency. I also understand that both conditions lower the red blood cell count in my body in different ways. Please correct me if I m wrong. However, what I m curious about is that are there any coupled effects? For example does having both further decrease my red blood cell count leading to lesser available oxygen for my body and therefore lower stamina when engaging in physical activities like sports.
Mon, 8 Jul 2013
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General & Family Physician,  's  Response
hi
Thanks for your query

i can feel your concerns

yes,you are quite right.both are hemolytic anaemias

beta thalassaemia is due to quantitative defect in beta globin chain while G6PD is enzyme deficiency

G6PD deficient individuals are usually normal unless they are exposed to certain drugs or foods.
As you are compound heterozygous for G6PD & thalassaemia ,so any exposure to these drugs and food will further decrease down your baseline haemoglobn,which is already low due to thalassaemia minor
Hope i have ansewered your query
i am available for your help
regards
Dr.Amna
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Suffer With Beta-Thalassemia Minor As Well As G6PD Deficiency. Are There Any Coupled Effects?

hi Thanks for your query i can feel your concerns yes,you are quite right.both are hemolytic anaemias beta thalassaemia is due to quantitative defect in beta globin chain while G6PD is enzyme deficiency G6PD deficient individuals are usually normal unless they are exposed to certain drugs or foods. As you are compound heterozygous for G6PD & thalassaemia ,so any exposure to these drugs and food will further decrease down your baseline haemoglobn,which is already low due to thalassaemia minor Hope i have ansewered your query i am available for your help regards Dr.Amna