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Dr. Andrew Rynne

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Suffering From Sickle Cell Disease. Antibiotics Not Working For UTI. Persisting Pain

Hello, I suffer from Sickle Cell Disease, SS. I extremely familiar with this disease, including the fact that infection may keep u n pain. I ve. Had four anti-biotics for an uti , non of them worked. So, I tried Diflucan ...nothing I try or the Docs try wrk, and as a result, I stay in pain. Not sure what to do beyond what I have.
posted on Sat, 7 Jul 2012
Twitter Tue, 10 Sep 2013 Answered on
Twitter Wed, 11 Sep 2013 Last reviewed on
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,
You have mentioned that you are suffering from urinary tract infection not responding to any of the antibiotics.
In this case, you need to get an urine culture done.
urine culture will isolate the causative organism for UTI.
After identifying the organism, most appropriate antibiotic can be identified by culture sensitivity.
Sickle cell anemia is known to cause a lesion in the kidneys called papillary necrosis.
Papillary necrosis is characterized by necrosis or destruction of the tips of the papillae of the kidney.
papillary necrosis cause blood in urine and pain.
Consult your hematologist for evaluation of your symptoms, relevant renal investigations and hence management.

Thanks and take care
Dr Shailja P Wahal

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Suffering From Sickle Cell Disease. Antibiotics Not Working For UTI. Persisting Pain

Hello and welcome to HCM, You have mentioned that you are suffering from urinary tract infection not responding to any of the antibiotics. In this case, you need to get an urine culture done. urine culture will isolate the causative organism for UTI. After identifying the organism, most appropriate antibiotic can be identified by culture sensitivity. Sickle cell anemia is known to cause a lesion in the kidneys called papillary necrosis. Papillary necrosis is characterized by necrosis or destruction of the tips of the papillae of the kidney. papillary necrosis cause blood in urine and pain. Consult your hematologist for evaluation of your symptoms, relevant renal investigations and hence management. Thanks and take care Dr Shailja P Wahal