Hello, I have studied your case. Feet swelling can be due to renal involvement. glucosamine medications are excreted by renal route but they may not be only reason for raised creatinine. You may need to do renal function test and pelvic ultrasound. Physiotherapy like ultrasound and tens will help, along with knee exercises Life style changes will help in reducing pain which include, LOAD REDUCTION: Protecting the joint from excessive load may slow down the rate of cartilage loss. It is also effective in relieving pain. The heavier you are, the more stress you put on your joints. Weight reduction for obese patients, wearing shock-absorbing shoes, avoiding activities like climbing stairs and using a walking stick are worthwhile. USING CANES: Assistive devices can make it easier to go about your day without stressing your painful joint. A cane may take weight off your knee or hip as you walk. Carry the cane in the hand opposite the leg that hurts. Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. If you are satisfied with answer do not forget to give rating to this answer. Wishing you good health. Take care