Dr Vineet, my name is Daniel Nicolae from Romania. I contacted you because i strongly need your oppinion regarding my blood analysis interpretation. I am diagnosticated with thalassemia major since i was 9 months old.
Before Nov 2008 my stats was good. 2 packs of blood every 4 weeks. My Hb level pre-trans 8-8.5, and after transf 10.5-11 ....sometimes even 12.
Well in November i changed to my chelator from Desferal to Exjade. My ferritine level before exjade was around 2200.
In the first weeks everything seemed to be fine. I was monitored weekly. After a few months i started to feel tired......I EVEN WAS SLEEPING IN THE AFTERNOON ( i almost never sleep in the afternoon).
Then my Hb level started to drop. Before transf. my Hb level 6-6.5. I started to take 2 packs every 3 weeks. Still my post-transf Hb level doesn't pass 8.5-9 ...... AFTER 3 PACKS OF BLOOD WITH 220ml each!
Then i changed to 3 packs every 2 weeks. The same result! Before transf Hb=6 and after 9 at most!
My doctors didn't say anything! They even were frustrated that i asked for extra blood! They said to remove my spleen!
In November 2010 doing some blood tests, my White Blood Cell counts were 3.2L ( normal range 4.0 - 9.0 ). Once i stopped Exjade, at my next blood tests my WBC=5.2L. My pre-trasnf. Hb level was now 7-7.5, and after transfusion 9.5-10 and even 11.6 after 3 packs of blood!
Now i am on Desferal, as my chelator. But yesterday after my last transfusion my WBC was again 3.4L this time.

I need to know what is happening to me, because my doctors only says that i should remove my spleen! I need your proffesional oppinion!
Thank you very much!
I will email my blood results from November, thouse with WBC = 3.2L at YYYY@YYYY if this is right, and specify that are mine!