Hi, Crystal meth, also known as methamphetamine, is a highly addictive stimulant drug that can have serious negative effects on the body. Some of the potential side effects of crystal meth use include loss of appetite, weight loss, insomnia, agitation and anxiety, increased heart rate and blood pressure, increased risk of heart attack and stroke, psychotic symptoms, such as paranoia and hallucinations, dental problems, skin problems, including acne, sores, and infections. The fatty substance you describe purging from your skin could be a side effect of crystal meth use. It is difficult to say for certain without more information or an examination, but the substance may be sebum, which is a natural oil produced by the body to lubricate and protect the skin. However, excessive production of sebum can lead to acne and other skin problems. In some cases, methamphetamine use can also cause a condition called methamphetamine-induced psychosis, which can include delusions, paranoia, and hallucinations. If you are experiencing any of these symptoms, it is important to seek medical attention immediately. It is concerning that you are experiencing pain and pressure from the congealed substance in your thighs, buttocks, and other areas. It is strongly recommended that you seek medical attention as soon as possible to address this issue. It is not recommended to try to drain the substance yourself, as this can lead to infection and other complications. In addition to seeking medical attention for your current symptoms, it is important to address your crystal meth use as soon as possible. Addiction is a serious disease that can have severe consequences on your physical and mental health, relationships, and overall quality of life. There are many resources available for those struggling with addiction, including support groups, therapy, and medical treatment. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician