Hi, Letrozole is a medication used to stimulate ovulation in women who are having difficulty conceiving. It works by inhibiting the production of estrogen, which can lead to increased production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. This in turn can help to induce ovulation. Like all medications, Letrozole can have side effects, although not everyone who takes it will experience them. Some of the potential side effects of Letrozole include: - Hot flashes - Headaches - Nausea - Fatigue - Dizziness - Mood changes - Vaginal dryness - Increased risk of multiple pregnancies (e.g., twins or triplets) It is important to note that Letrozole is contraindicated during pregnancy, as it can harm the developing fetus. Women who are using Letrozole to induce ovulation should be carefully monitored by their doctor to ensure that they do not become pregnant during treatment. In general, Letrozole is considered safe for most women when used as directed. However, it is important to discuss any concerns you may have with your doctor before starting treatment. They can provide you with detailed information about the benefits and risks of Letrozole, as well as any potential drug interactions or other precautions you should be aware of. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician