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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Allergic Reaction To Amoxicillin?

I am a 45 yo female, took last dose of Amoxicillin 875MG(BID x10days) this past Sat eve...Had no reaction at all while taking medication(Never sensitive to PCN in past)...woke up Sunday w/ itchy palms and soles of feet, than started w/ some generalized hives...took 50mg Benadryl last night, felt better...now today I am still having itchy palms & feet...
Tue, 8 Jul 2014
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General & Family Physician,  's  Response
Hello
You took Amoxicillin 875 mg twice in a day for 10 days and last day there develop itching over palm and soles .
Now note down the side effects of amoxicillin.
Hyperactivity, agitation , exfoliative dermatitis , URTICARIA , hypersensitivity vasculitis , nausea leucopenis , agranulocytosis .
Itching over palm and soles of feet were due to delayed and mild reaction ( hypersensitive ) of amoxiccillin.
Now you stopped the medicine , so that is good.
You took diphenhydramine 50 mg ( benadryl ) , this is also potent antihistamine , take it as necessary .
In my opinion this is sufficient for delayed and mild reaction of amoxycillin.
Good luck.
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What Causes Allergic Reaction To Amoxicillin?

Hello You took Amoxicillin 875 mg twice in a day for 10 days and last day there develop itching over palm and soles . Now note down the side effects of amoxicillin. Hyperactivity, agitation , exfoliative dermatitis , URTICARIA , hypersensitivity vasculitis , nausea leucopenis , agranulocytosis . Itching over palm and soles of feet were due to delayed and mild reaction ( hypersensitive ) of amoxiccillin. Now you stopped the medicine , so that is good. You took diphenhydramine 50 mg ( benadryl ) , this is also potent antihistamine , take it as necessary . In my opinion this is sufficient for delayed and mild reaction of amoxycillin. Good luck.