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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Behavioral Issues While On Prednisone, Valium And Oxycodone?

Hello Dr. Andrews. I am writing you because I am very concerned about a family member and her use of multiple prescriptions. She is currently taking Prednisone, Valium, Oxycodone, Adderall and sleeping pills (not sure which kind) and she drinks alcohol frequently. It s very clear to me she has developed an extreme addiction and her behavior is starting to become more erratic. Do you have any information on the potential effects of mixing these types of drugs? I want to speak with her but want to make sure I have compelling information to share with her rather than my opinion of how she is behaving .Thank you. XXXX
Tue, 18 Feb 2020
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General & Family Physician,  's  Response
Hi,

Following harmful interactions can occur if the above medications are taken together starting with the most serious one:

1. Taking Oxycodone with other drugs that also cause central nervous system depression like Valium or any sleeping pills or consuming alcohol can lead to serious side effects including respiratory distress, coma, and even death. She may need a dose adjustment or alternate effective medications to treat her illness. Beside she should avoid consuming alcohol.

2. Drinking alcohol while on Adderall can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. She should also avoid or limit the use of alcohol while being treated with Adderall. Let her doctor know if she experiences severe or frequent headaches, chest pain, and/or a fast or pounding heartbeat.

There is no other documented harmful interactions between Prednisone and other prescribed medications.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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What Causes Behavioral Issues While On Prednisone, Valium And Oxycodone?

Hi, Following harmful interactions can occur if the above medications are taken together starting with the most serious one: 1. Taking Oxycodone with other drugs that also cause central nervous system depression like Valium or any sleeping pills or consuming alcohol can lead to serious side effects including respiratory distress, coma, and even death. She may need a dose adjustment or alternate effective medications to treat her illness. Beside she should avoid consuming alcohol. 2. Drinking alcohol while on Adderall can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. She should also avoid or limit the use of alcohol while being treated with Adderall. Let her doctor know if she experiences severe or frequent headaches, chest pain, and/or a fast or pounding heartbeat. There is no other documented harmful interactions between Prednisone and other prescribed medications. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician