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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Decrease In Hemoglobin Levels In A Child?

My daughter is 5 month old, her hemoglobin drops drastically.. after transfusion within a week it goes down to 7.1 or lower sometime. they did all kind of test to see any kind of anemia but Dr. saying they dont have answer why her hemoglobin is dropping...
posted on Thu, 13 Mar 2014
Twitter Sun, 18 Sep 2016 Answered on
Twitter Mon, 19 Sep 2016 Last reviewed on
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Pediatrician,  's  Response
it's very important to differentiate this anemia from any type of hemolytic anemia , which means the red blood cells being destroyed , in simple words the causes of profound anemia to this child are few :
either a profound destruction : which causes increase biliruben along with reticulocyte count ( immature red blood cells , positive direct coombs test )
or the most likely here is the inability of the bone marrow to produce red blood cells either due to infection ( such as Parvovirus b19) which causes a disease called ( red cell Aplasia ) in which the number of RBCS are very few .
OR what is cakked transient erythroblastopenia of childhood , which causes the red cells to markedly decrease in number ( pure red cell Aplasia)
bone marrow biopsy is some times needed to exclude other causes , but usually the transient erythroblastopenia of childhood requires one blood transfusion or 2 at max and then the child improves , keeping in mind it's the most common cause of pure red cell Aplasia in children
I hope this helps
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What Causes Decrease In Hemoglobin Levels In A Child?

it s very important to differentiate this anemia from any type of hemolytic anemia , which means the red blood cells being destroyed , in simple words the causes of profound anemia to this child are few : either a profound destruction : which causes increase biliruben along with reticulocyte count ( immature red blood cells , positive direct coombs test ) or the most likely here is the inability of the bone marrow to produce red blood cells either due to infection ( such as Parvovirus b19) which causes a disease called ( red cell Aplasia ) in which the number of RBCS are very few . OR what is cakked transient erythroblastopenia of childhood , which causes the red cells to markedly decrease in number ( pure red cell Aplasia) bone marrow biopsy is some times needed to exclude other causes , but usually the transient erythroblastopenia of childhood requires one blood transfusion or 2 at max and then the child improves , keeping in mind it s the most common cause of pure red cell Aplasia in children I hope this helps