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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Difficulty In Walking & Climbing The Stairs?

67 yr old female; positive ANA Screen; Sed Rate elevated at 40; ALT 76; AST 65; ANA Titer 1:256 with mixed homogeneous, speckled and nucleolar ANA staining observed. Anti-DNA, Dbl Strand, C-Reactive Protein, Rheumatoid Factor and Hepatitis B & C all within normal ranges. 2011 CT of abdomen showed multiple scattered attenuation lesions within liver, sub-centimeter in size-likely cysts or hemangiomas. Dr. put me on plaquenil and is having an abdominal ultrasound done as well. Have great difficulty walking and climbing stairs. Is the ANA screen and sed rate related to the increased ALT and AST or am I dealing with two different things?
posted on Tue, 9 Sep 2014
Twitter Thu, 28 May 2015 Answered on
Twitter Fri, 29 May 2015 Last reviewed on
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Orthopaedic Surgeon,  's  Response
hi
if some auto-immune is suspected then ANA and AST ALT may be related.I may suggest anti-mitochondrial antibody test also to rule out auto-immune liver disease, which probably, if your doctor thinks necessary may get done
With liver damage shown by ALT AST, exertion is there on climbing and walking and definitely complete rest with more of glucose diet may be indicated to prevent malaise and weakness.
wish you good luck with ultrasound and tests and wish good health
Regards
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What Causes Difficulty In Walking & Climbing The Stairs?

hi if some auto-immune is suspected then ANA and AST ALT may be related.I may suggest anti-mitochondrial antibody test also to rule out auto-immune liver disease, which probably, if your doctor thinks necessary may get done With liver damage shown by ALT AST, exertion is there on climbing and walking and definitely complete rest with more of glucose diet may be indicated to prevent malaise and weakness. wish you good luck with ultrasound and tests and wish good health Regards