What Causes Knots And Redness On The Lower Leg?

I have three dime sized knots on my inner calf just above my ankle. My ankle, just above the bone has a 2 square red area. Both the knots and the redness are painful to the touch, I also get sharp pains at random times too. I have been to the doctor a blood test for clots was ran and I was put on antibiotics last Friday...but I am still the same, nothing seems to have changed, for better or worse. I am not sure if I should go back to our family doctor or give the 7 days of antibiotics more time to do their job. I have found that a warm towel helps with the pain, and that has allowed me to sleep. Thanks for your help.