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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Pain And Swelling In Legs?

My husband has been on Coumadin for a number of years. Most recently his pt has been all over the board. He is currently taking 2.5 mgs 5 days a week, so 2 days a week he is taking nothing. About 3 wks ago, his right foot swelled up, he had considerable pain, they did an x-ray, no broken bones, they put him in a boot and in a couple of days, the swelling went down & the pain went away...2 days ago, it started over now pain in his elbow and swelling in his elbow and hand, right one. He is also taking Crestor, 10 mgs per day. Could this be DVT??? or a reaction to the statin which he has been on again for about a yr...he does not tolerate that well....didn t take it for a number of yrs due to pain in his joints...
posted on Fri, 14 Mar 2014
Twitter Thu, 7 Sep 2017 Answered on
Twitter Fri, 8 Sep 2017 Last reviewed on
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Orthopaedic Surgeon,  's  Response
Hi, I had gone through your question and understand your concerns.

It is not likely to be DVT as your husband already on Continuous anticoagulation and DVT is rare in the elbow

If I were your husband treating Doctor for this case of recurrent swelling in different parts of the body with pain, I would come up with three possibilities, these include:

1- Side effect off Coumadin as this drug is anticoagulant and its overdose may lead to multiple hematomas and this could be assessed by bleeding investigations and prothrombin activity and the treatment is dose adjustment of the drug.

2-Autoimmune disorders should be excluded by doing the following investigations(Rheumatoid factor, ANA,Anti CCP,ESR,CRP and CBC)

3-Gouty arthritis should be excluded by doing serum uric acid.
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What Causes Pain And Swelling In Legs?

Hi, I had gone through your question and understand your concerns. It is not likely to be DVT as your husband already on Continuous anticoagulation and DVT is rare in the elbow If I were your husband treating Doctor for this case of recurrent swelling in different parts of the body with pain, I would come up with three possibilities, these include: 1- Side effect off Coumadin as this drug is anticoagulant and its overdose may lead to multiple hematomas and this could be assessed by bleeding investigations and prothrombin activity and the treatment is dose adjustment of the drug. 2-Autoimmune disorders should be excluded by doing the following investigations(Rheumatoid factor, ANA,Anti CCP,ESR,CRP and CBC) 3-Gouty arthritis should be excluded by doing serum uric acid.