I am 50 yo F with Hypothyroidism, never hospitalized. I take 112 mcg synthroid. My problem started a year ago and recently become hard to tolerate. I ve been to see my PCP 5X. I have intense/chronic anal itching, mostly right around the anal opening, sometimes both inside cheeks itch. I have a slimy discharge that I wipe constantly. On my right cheek, right at the edge I have a very hard painful lump about 1 X3 , hot to the touch. Now I have developed a throbbing pain right inside the anal openng. My doc has given me nizoral, hydrocortisone, diflucan but has never physically looked at my rear. The lump started two days ago and I can barely stand the pain. Please tell me what can I do to ease this pain and the itch which is driving me to the brink of sanity. Thank you so very much for your advice.