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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is Causing IgG And GFR To Be Very Low?

My IgG is mod low.My dr said I wasn t making antibodies either.Now it shows some protein in my urine and mildly elevated Kappa/Lamba ratio of 18.25. My GFR test was 60- which I assume for a 30 year old thats a bit low. What could be the cause? I ve had ITP, GERD and fibromyalgia for years.
posted on Tue, 11 Mar 2014
Twitter Fri, 21 Nov 2025 Answered on
Twitter Tue, 2 Dec 2025 Last reviewed on
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Nephrologist 's  Response
Hello,

If you have proteinuria, you should do this test: 24 hour urine collection for protein and creatinine, ANA, Anti-dsDNA, C3, and C4...

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Maryam Miri, Nephrologist
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What Is Causing IgG And GFR To Be Very Low?

Hello, If you have proteinuria, you should do this test: 24 hour urine collection for protein and creatinine, ANA, Anti-dsDNA, C3, and C4... Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Maryam Miri, Nephrologist