patient is my daughter-in-law and her dad is extremely disturbed by diagnosis. she has suffered from severe pain to left knee for over 8 wks and finally went to physician. x-ray of pained area revealed lesion of tibia... she is very heavy (51 year old female, 330#, 5 9 ) and doesn t take care of herself. what should we expect. dr has recommended mri. our concern is that cancer runs in her mom s family. mom, grandparents and brother all died of cancer (bone, breast, stomach, colon, back). though she has never had cancer, in your opinion, should we be extremely concerned. how can we help her????