Hi, my husband has been on medication Methotrexate for almost 18 months for the treatment of Vasculitis in the optical part of the brain . Not sure how to explain it. He suffered a stoke and was left with eye sight impairment in his left side of both eyes plus now suffers with, type 2 diabetes, high blood pressure, now approx 42% kidney function. My question is, Is there an alternative to using this strong medication which is now effecting him and making him unwell? His specialist has just asked him not to take it for two weeks before recommencing to see how he reacts. Further discussion to be had in 3 month concerning all of this.