I am male, 61, 6’2”, 343#. I have been completely monogamous for more than 40 years. I have osteopenia, high cholesterol, high blood pressure, and low testosterone all controlled by medication. Stage 3 CKD, stabilized. Osteoarthritis & chronic gouty arthritis are problems in knees, hips and lower back. I do not use NSAIDs due to kidneys. I do not have diabetes (near perfect A1c & glucose tolerance). I am on long term Keflex due to chronic staff infections. Gradually (over past 2 years?) my pre-ejaculatory fluid has become extremely bitter to my wife and developed an anesthetic effect on her mouth or genitalia as well as my genitalia . This has become sufficient as to prevent climax except by masturbation, and then only with great care to avoid contact between my genitalia my pre-ejaculatory fluid. The flow of my pre-ejaculatory fluid is almost constant and has increased in volume to exceed that of my ejaculation. PSA is near below 2 and manual exam is normal. Any suggestions other than forgetting our sex life?