Hello, unfortunately, your question does not provide the necessary details to understand your situation and treatment. For example, you haven t mentioned the reason that prednisolone was prescribed. I do not even know whether you re talking about local treatment (creams) or systemic treatment (pills). I can only make a general comment about prednisolone treatment. Treatment with corticosteroids (like prednisolone) may affect the way the body modulates complex hormonal systems. When a patient takes corticosteroids more often than once every morning, the risk is even higher. Prednisolone can be used once per day, or many times per day depending on the disorder. Therefore there is no right or wrong dosage... I hope I ve answered your question. Please let me know if you need further assistance. Kind Regards, Dr Panagiotis Zografakis Internal Medicine Specialist