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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Ingestion Of Multiple Medicines Make A Person Drowsy?

I take the following medications and I am like a zombie, labetalol HCL 200 2 x a day. Levothyroxine 150 1 x a day, and Amlodipine-benazepril 5-10 MG 1 x a day, at morning taking levothyroxine first and after eating taking the other two. At night I take, Pantoprazole 40 1 x a day, Atorvastatin calcium 80 MG 1 x a day, Pramipexole 0.25 MG 1 x a day, and Labetalol HCL 200. Are the way that I am taking these medications causing me to be tired and sleepy at all times? Thanks in advance for your help.
Thu, 3 Mar 2016
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Addiction Medicine Specialist,  's  Response
Labetalol and Pramipexole have direct links to drowsiness. Pramipexole gets into the brain to be able to work and has a well known side effect of drowsiness. While anything including water, food and air are 'associated' with drowsiness, actually having a REASON to make someone drowsy OR a repeated connection to drowsiness is more important as a connection, so those are the drugs taht are likely to be the cause. Changing or holding off the medicines and seeing if the drowsiness changes would also tend to show which is the cause.
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Will Ingestion Of Multiple Medicines Make A Person Drowsy?

Labetalol and Pramipexole have direct links to drowsiness. Pramipexole gets into the brain to be able to work and has a well known side effect of drowsiness. While anything including water, food and air are associated with drowsiness, actually having a REASON to make someone drowsy OR a repeated connection to drowsiness is more important as a connection, so those are the drugs taht are likely to be the cause. Changing or holding off the medicines and seeing if the drowsiness changes would also tend to show which is the cause.