I am 53 I am 5'6' and weigh 158 I was started on Norvasc 5mg and losartan 100mg in April. Had previously been on lisinopril and spirolatone, anyway when labs checked in September I had elevated liver fucntion tests, I asked the doctor then if it could be result of switching to the new medicine as I had not had elevated liver tests when on the other medicine. I was switched off the other due to how it was making me feel. I was left on the norvasc and losartan and at the same doses. The doctor had me return Nov 8 to check liver function tests and they had gone up I belive the alk phos was at 240, and alt or ast had went for 54 to 68. A hepatitis panel was done and was negative. I had ultrasounds done on liver, pancreas, bile duct and gall bladder and these were perfectly normal. I have no abdominal pain, no nausea, no vomiting, no loose stools no abnormal stools, no fever. I again asked the doctor if medicine could be cause as I had looked on internet and found that norvasc has caused hepatitis severe enough to lead to hospitalization. When I told him this he then looked it up on his pda and found that i was correct and that losartan also could affect the liver so these were both stopped. I have refused to take anything until I go back to get liver rechecked the 12th of dec. My blood pressures have been ok. Today it was 128/88. My concern is will by liver be permanently affected and will liver functions return to normal