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Can Sinemet And Targin After Hip Surgery Cause Confusion And Hallucinations?

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Posted on Thu, 7 May 2015
Question: Can Sinemet 4times per day given with Targin following hip surgery ina patient 80 years old cause the patient to be very confused and at time Hallucinations ? allergy to morphine after operation .
doctor
Answered by Dr. Dr. Rovena (24 minutes later)
Brief Answer:
yes,they can be taken together.

Detailed Answer:
Hello.

Welcome to Healthcare Magic.

Yes, Sinemet and Targin can be taken together.There is no significant interaction between these drugs that would explain any possible effect.
The actual symptoms doesn't seem to be related with the combination of the drugs .
Hallucinations (particularly visual hallucinations) and confusion are common side effects of Sinemet .You should discuss this with her treating doctor .He may decide to lower the dose of the treatment.

Hope it helps.
Let me know if you need further help or need further clarifications.

Kind regards,
Dr.Rovena
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Rovena (41 minutes later)
Full Storey which may help . Hip operation was on 9 04 2015 returned from surgery 3 hrs later in good spirits ,had spinal Anaesthetic next day very confused following some Morphine then ok in following days .Now in a Rehab area and being given Endone an opiate and now Targin another opiate with some panadol . yesterday, major confusion and has no idea where she is ,doctors do not know what is going on,doing blood tests and checking UTI .
She is taking Sinemet for Parkinson's disease and Cortizone for Polymyalgia .
With the confusion she will not do the Physio nor eat so not helping recovery. Any ideas would be appreciated ,Regards Richard
doctor
Answered by Dr. Dr. Rovena (1 hour later)
Brief Answer:
detailed below.

Detailed Answer:
Hello again.

In patients with Parkinson disease ,every stressful situation like surgeries,infections carry the risk of precipitating episodes of hallucinations and confusion.
None of the drugs that she has been taking has any interaction with the Parkinsons's medication that would explain the symptoms.

The doctor with do some tests to exclude any pathological cause like infections,electrolyte imbalance,dehydration etc.
If all the tests are normal ,they may decide to lower the dose of Sinemet or decide to stop the treatment until the episode of psychosis resolves.

Let me know if you have any other question or doubts to clarify.

Take care.
Dr.Rovena



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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Rovena

General & Family Physician

Practicing since :2013

Answered : 1243 Questions

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Can Sinemet And Targin After Hip Surgery Cause Confusion And Hallucinations?

Brief Answer: yes,they can be taken together. Detailed Answer: Hello. Welcome to Healthcare Magic. Yes, Sinemet and Targin can be taken together.There is no significant interaction between these drugs that would explain any possible effect. The actual symptoms doesn't seem to be related with the combination of the drugs . Hallucinations (particularly visual hallucinations) and confusion are common side effects of Sinemet .You should discuss this with her treating doctor .He may decide to lower the dose of the treatment. Hope it helps. Let me know if you need further help or need further clarifications. Kind regards, Dr.Rovena