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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Tab Oflox Oz Taken By Mother After Delivery Lead To Transient Hypothyroidism In Newborn?

Hi Doctor, Does Tab Oflox Oz taken by Mother after delivery for 5 days lead to transient hypothyroidism in newborn? My newborn daughter 12 days old shows very high TSH (ECLIA) =591 micIU/mL, Low FT4 (ECLIA) - 023 ng/dL Thyroid scan shows mildly enlarged thyroid gland, %uptake of tracer by gland: 6.5%, homogenious uptake in both lobes, No salivary uptake. Please advise if I should start Thyroxine 38.5 mcg immediately for baby. baby weight is 3.1 Kg, height 49cm, passing motions, urine, no constipation, no jaundice, no other symptoms (APGAR score at 1& 5: 9/10, 9/10) I need to consult peadiatric endocrynologist, please let me know if available Thanks, KK
Wed, 8 Apr 2020
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General & Family Physician 's  Response
Hi,

This tablet does not cause transient hypothyroidism in the newborn. Based on the results of thyroid function tests your baby seems to be suffering from congenital hypothyroidism apparently due to underdeveloped thyroid gland which cannot make a normal amount of thyroid hormone.

The prescribed thyroxine should be started immediately to prevent mental and growth retardation and the tests are checked every 1 to 2 months up to 6 months of age and then every 2 to 3 months thereafter to check the response of the treatment.

Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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Does Tab Oflox Oz Taken By Mother After Delivery Lead To Transient Hypothyroidism In Newborn?

Hi, This tablet does not cause transient hypothyroidism in the newborn. Based on the results of thyroid function tests your baby seems to be suffering from congenital hypothyroidism apparently due to underdeveloped thyroid gland which cannot make a normal amount of thyroid hormone. The prescribed thyroxine should be started immediately to prevent mental and growth retardation and the tests are checked every 1 to 2 months up to 6 months of age and then every 2 to 3 months thereafter to check the response of the treatment. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician