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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Excessive Swelling, Fluid In Knees. Have Auto Immune Hepatitis. Taking Prednisone, Imuran. Medicine To Reduce Swelling?

I have auto immune hepatitis, my doctor has had me on Prednisone and Imuran for about 3 months. I started on 20 mg.,and I have tapered down to 7.5. My enzyme levels are normal, but I am having problems with swelling excessively. I am having problems with my knees with fluid backup. What can I do to help with the swelling?
posted on Thu, 24 Oct 2013
Twitter Fri, 25 Oct 2013 Answered on
Twitter Fri, 25 Oct 2013 Last reviewed on
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Allergist and Immunologist 's  Response
Hello,

Swelling is the major side effect of steroid medications.
You will need a ECG, 2D-ECHO to ensure there is no heart component (heart failure) as cause of swelling.
Secondly I hope the kidney function is normal.
If both of above are ok, then a low dose diuretic (water tablet) will lower the swelling.
Ensure the uruc acid level is normal.

Best Wishes.
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Excessive Swelling, Fluid In Knees. Have Auto Immune Hepatitis. Taking Prednisone, Imuran. Medicine To Reduce Swelling?

Hello, Swelling is the major side effect of steroid medications. You will need a ECG, 2D-ECHO to ensure there is no heart component (heart failure) as cause of swelling. Secondly I hope the kidney function is normal. If both of above are ok, then a low dose diuretic (water tablet) will lower the swelling. Ensure the uruc acid level is normal. Best Wishes.