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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Need Help In Interpreting PAP Smear Test Result. Report Saying Benign Cellular Changes, Predominance Of Coccobacilli In Vaginal Flora, Severe Inflammation

Hello can you interpret my PAP Smear result: Specimen adequacy - satisfactory for evaluation, Descriptive Diagnosis: Benign Cellular Changes Infection: predominance of coccobacilli consistent with shift in vaginal flora , Inflammation (includes atypical repair) Comments: Severe inflammation and abundant neutrophils. Hormonal evaulation compatible with age and history, maturation index: superficial 100%, intermediate 0% parabasal 0%. Thanks in advance for answering doc.
posted on Sun, 9 Sep 2012
Twitter Thu, 21 Apr 2016 Answered on
Twitter Fri, 22 Apr 2016 Last reviewed on
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OBGYN,  's  Response
Hello,
I have gone through your query and understood the concern. The predominance of coccobacilli suggests presence of bacterial vaginosis. Shift in the vaginal flora can be seen when the pH of the vagina changes as in pregnancy and menopause. Infections can also cause this change. The infection has led to the presence of neutrophils. Maturation index is useful to understand the hormone effect on the vaginal epithelium. The reading may be erratic when there is overlying infection. High superficial cells in the index suggests effect of estrogen unopposed by progesterone. This can happen with hormone imbalance, menopause and estrogen treatment to the vagina. Hope this helps.
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Need Help In Interpreting PAP Smear Test Result. Report Saying Benign Cellular Changes, Predominance Of Coccobacilli In Vaginal Flora, Severe Inflammation

Hello, I have gone through your query and understood the concern. The predominance of coccobacilli suggests presence of bacterial vaginosis. Shift in the vaginal flora can be seen when the pH of the vagina changes as in pregnancy and menopause. Infections can also cause this change. The infection has led to the presence of neutrophils. Maturation index is useful to understand the hormone effect on the vaginal epithelium. The reading may be erratic when there is overlying infection. High superficial cells in the index suggests effect of estrogen unopposed by progesterone. This can happen with hormone imbalance, menopause and estrogen treatment to the vagina. Hope this helps.