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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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With S. Typhi O 1:320 And S. Typhi H 1;160 What Is The Treatment?

Mamuna aged 16yrs has infective psychosis and has been on ciprofloxacin 500mg 12hrly for about 4 weeks. The widal titres have however remained high - s. typhi o 1:320 and s. typhi H 1;160. He has been re-admitted and my question is how best do we treat her?
Tue, 19 Dec 2017
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Neurologist 's  Response
Hello Mamuna!

I would recommend switching to another antibiotic, probably doxycycline combined with Ceftriaxone.

Regarding the psychosis, an anti-psychotic like olanzapine could be helpful!

A new brain MRI is also necessary.

Hope you will find this answer helpful!

Best wishes, Dr. Aida
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With S. Typhi O 1:320 And S. Typhi H 1;160 What Is The Treatment?

Hello Mamuna! I would recommend switching to another antibiotic, probably doxycycline combined with Ceftriaxone. Regarding the psychosis, an anti-psychotic like olanzapine could be helpful! A new brain MRI is also necessary. Hope you will find this answer helpful! Best wishes, Dr. Aida