HealthCareMagic is now Ask A Doctor - 24x7 |

Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction
Article Home Adult and Senior Health Keratolysis Exfoliativa Congenita

Keratolysis Exfoliativa Congenita

Keratolysis exfoliativa congenita is a rare skin disorder characterized by superficial peeling of the skin of the palms and soles in the absence of inflammation.


Keratolysis Exfoliativa Congenita also called as Peeling skin syndrome is an extremely rare inherited disorder characterized by continual, spontaneous skin peeling (exfoliation). Other findings may include reddening of the skin (erythema) and itching (pruritus).It starts as pinhead-sized white spots that gradually extend peripherally, forming anular thin scales, in the absences of inflammation.


  • Keratolysis Exfoliativa Congenita
  • Familial Continuous Skin Peeling
  • Deciduous Skin
  • Acral Peeling Skin Syndrome
  • Skin Peeling Syndrome 


One group working on this disorder distinguishes between it as two types of Acral Peeling Skin Syndrome:

  • a non-inflammatory form called type A
  • an inflammatory form known as type B

Type B is associated with congenital erythroderma, a condition in which the skin has an intense red color. There is mounting evidence that the inflammatory type B is a variant of Netherton syndrome.

Signs and symptoms

  • White spot on palms and soles
  • Thin annular scaling
  • Reddening of the skin
  • Itching
  • Absence of Inflammation 


There is no specific treatment for this disease supportive and symptomatic treatment is given.